Hydrochloric Acid → [2-bromo-6-(tert-butoxycarbonyl)-3-cyclohexyl-1H-indol-1-yl]acetic acid

HRID 948038Notes

Reaction equation

HRID 948038 reaction equation
[Br:1][c:2]1[n:3]([CH2:24][C:25](=[O:26])[O:27][CH3:28])[c:4]2[cH:5][c:6]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:7][cH:8][c:9]2[c:10]1[CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1.[ClH:29].[OH2:30]>>[Br:1][c:2]1[n:3]([CH2:24][C:25](=[O:26])[OH:27])[c:4]2[cH:5][c:6]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:7][cH:8][c:9]2[c:10]1[CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 68511006tert-butyl 2-bromo-3-cyclohexyl-1-(2-methoxy-2-oxoethyl)-1H-indole-6-carboxylate

Product 1

HCID 68509336[2-bromo-6-(tert-butoxycarbonyl)-3-cyclohexyl-1H-indol-1-yl]acetic acid

Sources & evidence

ORD record
ord-71893aeefa6d4475b8037ba6abd20665
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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