Toluene → 1-(4-Bromopyridin-2-yl)cyclobutane-1-carbonitrile
Reaction equation
[Br:11][c:12]1[cH:13][c:14]([F:18])[n:15][cH:16][cH:17]1.[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[CH:19]1([C:23]#[N:24])[CH2:20][CH2:21][CH2:22]1.[Li+:1]>>[Br:11][c:12]1[cH:13][c:14]([C:19]2([C:23]#[N:24])[CH2:20][CH2:21][CH2:22]2)[n:15][cH:16][cH:17]1Participants
6
Sources & evidence
- ORD record
- ord-908aee9a026245d18ce9d1342ea131a8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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