Dichloromethane → 4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-3-ylmethoxy)quinazoline

HRID 948058Notes

Reaction equation

[CH2:50]([P:51]([CH2:52][CH2:53][CH2:54][CH3:55])[CH2:56][CH2:57][CH2:58][CH3:59])[CH2:60][CH2:61][CH3:62].[CH2:63]([Cl:64])[Cl:65].[CH3:41][N:42]1[CH2:43][CH:44]([CH2:48][OH:49])[CH2:45][CH2:46][CH2:47]1.[Cl:19][c:20]1[cH:21][c:22]([F:40])[c:23]([NH:24][c:25]2[n:26][cH:27][n:28][c:29]3[cH:30][c:31]([OH:37])[c:32]([O:35][CH3:36])[cH:33][c:34]23)[cH:38][cH:39]1.[N:1]([C:2]([N:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1)=[O:9])=[N:10][C:11]([N:12]1[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]1)=[O:18]>>[Cl:19][c:20]1[cH:21][c:22]([F:40])[c:23]([NH:24][c:25]2[n:26][cH:27][n:28][c:29]3[cH:30][c:31]([O:37][CH2:48][CH:44]4[CH2:43][N:42]([CH3:41])[CH2:47][CH2:46][CH2:45]4)[c:32]([O:35][CH3:36])[cH:33][c:34]23)[cH:38][cH:39]1