Chloroform → HCID 19390724, compound

HRID 948104Notes

Reaction equation

HRID 948104 reaction equation
[C:22]([NH2:23])([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29].[CH:36]([Cl:37])([Cl:38])[Cl:39].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6](=[O:21])[n:7]3[c:8]([n:9][c:10]2[cH:11]1)[C:12](=[O:20])[c:13]1[cH:14][c:15]([F:19])[cH:16][cH:17][c:18]1-3.[LiH:30].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[c:2]1([NH:23][C:22]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[cH:3][cH:4][c:5]2[c:6](=[O:21])[n:7]3[c:8]([n:9][c:10]2[cH:11]1)[C:12](=[O:20])[c:13]1[cH:14][c:15]([F:19])[cH:16][cH:17][c:18]1-3

Participants

6

Reactant 5

HCID 6212ChloroformHCID 6228DimethylformamideHCID 77922tert-Butyl carbamateHCID 4786513,8-Difluoro-indolo(2,1-b)quinazoline-6,12-dioneHCID 178506917HCID 178506917, compound

Product 1

HCID 19390724HCID 19390724, compound

Sources & evidence

ORD record
ord-74fbb814d42747f298261d3fb96c363b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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