Dichloromethane → 4-(Pyridin-2-yl)piperidine-4-carbonitrile
Reaction equation
[C:1](#[N:2])[C:3]1([c:16]2[n:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:4][CH2:5][N:6]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[CH2:7][CH2:8]1.[Cl:29][CH2:30][Cl:31].[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28]>>[C:1](#[N:2])[C:3]1([c:16]2[n:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:4][CH2:5][NH:6][CH2:7][CH2:8]1Participants
4
Sources & evidence
- ORD record
- ord-2c964f538e7b4204b85fe022cc12580f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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