Hydrochloric Acid → 4-[4,4-Bis(4-fluorophenyl)butyl]-2-piperazinemethanol

HRID 948123Notes

Reaction equation

HRID 948123 reaction equation
[ClH:30].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][CH2:10][CH2:11][N:12]2[CH2:13][CH:14]3[N:15]([CH2:16][CH2:17]2)[C:18]([CH3:21])([CH3:22])[O:19][CH2:20]3)[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[cH:6][cH:7]1.[OH2:31]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][CH2:10][CH2:11][N:12]2[CH2:13][CH:14]([CH2:20][OH:19])[NH:15][CH2:16][CH2:17]2)[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 212957107-[4,4-bis(4-fluorophenyl)butyl]hexahydro-3,3-dimethyl-1H-oxazolo[3,4-a]pyrazine

Product 1

HCID 212956744-[4,4-Bis(4-fluorophenyl)butyl]-2-piperazinemethanol

Sources & evidence

ORD record
ord-72f4372891184d05ac5b1b6aafa6fd74
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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