Dichloromethane → 5-{1-[4-(3-Methyl-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-thiophene-2-sulfonic Acid Amide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[n:15][cH:16][n:17](-[c:19]3[n:20][c:21]([C:36]([F:37])([F:38])[F:39])[cH:22][c:23](-[c:25]4[cH:26][c:27]([CH3:35])[c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]4)[n:24]3)[cH:18]2)[cH:12][cH:13]1.[Cl:47][CH2:48][Cl:49].[F:40][C:41]([F:42])([F:43])[C:44]([OH:45])=[O:46]>>[NH2:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[n:15][cH:16][n:17](-[c:19]3[n:20][c:21]([C:36]([F:37])([F:38])[F:39])[cH:22][c:23](-[c:25]4[cH:26][c:27]([CH3:35])[c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]4)[n:24]3)[cH:18]2)[cH:12][cH:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-54eaeeb3231f4ac7a8940a5aad386b13
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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