Dichloromethane → 1-(Oxetan-3-yl)piperazine

HRID 948341Notes

Reaction equation

[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]2[CH2:22][O:23][CH2:24]2)[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[Cl:25][CH2:26][Cl:27].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][N:18]([CH:21]2[CH2:22][O:23][CH2:24]2)[CH2:19][CH2:20]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 59605443Tert-butyl 4-(oxetan-3-YL)piperazine-1-carboxylate

Product 1

HCID 574162871-(Oxetan-3-yl)piperazine

Sources & evidence

ORD record: ord-1614b542fbd24f699cc3fa190c27b10b
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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