Dichloromethane → 6-Oxa-9-azaspiro(4.5)decane

HRID 948417Notes

Reaction equation

[CH2:1]1[CH2:2][CH2:3][CH2:4][C:5]12[O:6][CH2:7][CH2:8][N:9]([C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[CH2:10]2.[Cl:25][CH2:26][Cl:27].[OH:18][C:19]([C:20]([F:21])([F:22])[F:23])=[O:24]>>[CH2:1]1[CH2:2][CH2:3][CH2:4][C:5]12[O:6][CH2:7][CH2:8][NH:9][CH2:10]2

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 15143399-Boc-6-oxa-9-azaspiro[4.5]decane

Product 1

HCID 224171726-Oxa-9-azaspiro(4.5)decane

Sources & evidence

ORD record: ord-d35232af667c421d9b526b14d4c66810
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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