HRID948426

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID11776

Triphenylphosphine

C18H15P

HCID12308

3-Bromo-1-propanol

C3H7BrO

HCID220568

Diethyl azodicarboxylate

C6H10N2O4

结构：COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1O

HCID135530832

未命名化合物

PRODUCTS

生成物

结构：COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCBr

HCID58960242

7-(3-Bromopropoxy)-4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinazoline

C21H19BrFN3O3

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a9bd232356fa44f18a55b667a1a5d312
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:57][CH2:58][CH2:59][CH2:60][OH:61].[CH2:62]([Cl:63])[Cl:64].[F:13][c:14]1[c:15]2[cH:16][c:17]([CH3:37])[nH:18][c:19]2[cH:20][cH:21][c:22]1[O:23][c:24]1[n:25][cH:26][n:27][c:28]2[cH:29][c:30]([OH:36])[c:31]([O:34][CH3:35])[cH:32][c:33]12.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1>>[F:13][c:14]1[c:15]2[cH:16][c:17]([CH3:37])[nH:18][c:19]2[cH:20][cH:21][c:22]1[O:23][c:24]1[n:25][cH:26][n:27][c:28]2[cH:29][c:30]([O:36][CH2:60][CH2:59][CH2:58][Br:57])[c:31]([O:34][CH3:35])[cH:32][c:33]12