Toluene → Ethyl 4,4-difluoro-3-oxo-2-(piperidin-1-ylmethylidene)butyrate
Reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[F:21][CH:22]([C:23](=[O:24])[F:25])[F:26].[N:1]1([CH:7]=[CH:8][C:9](=[O:10])[O:11][CH2:12][CH3:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH:7]=[C:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[C:23]([CH:22]([F:21])[F:26])=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
5
Sources & evidence
- ORD record
- ord-5331cd8598cd42f1925880669e89d436
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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