Ethyl Acetate → 7-(2-Chloro-4-iodophenylamino)-5,6-difluoro-3-methyl-2,3-dihydro-isoindol-1-one
Reaction equation
[CH3:30][CH2:31][O:32][C:33]([CH3:34])=[O:35].[Cl:1][c:2]1[c:3]([NH:8][c:9]2[c:10]([F:21])[c:11]([F:20])[cH:12][c:13]3[c:17]2[C:16](=[O:18])[NH:15][CH:14]3[CH3:19])[cH:4][cH:5][cH:6][cH:7]1.[O:22]=[C:23]1[N:24]([I:29])[C:25](=[O:26])[CH2:27][CH2:28]1>>[Cl:1][c:2]1[c:3]([NH:8][c:9]2[c:10]([F:21])[c:11]([F:20])[cH:12][c:13]3[c:17]2[C:16](=[O:18])[NH:15][CH:14]3[CH3:19])[cH:4][cH:5][c:6]([I:29])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-8befd4efa1654c3e8951d6e86a5a6cb6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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