1-Butanol → N4-(4-Methoxy-phenyl)-N2,N4-dimethyl-N2-(2-methylamino-ethyl)-quinazoline-2,4-diamine

HRID 948838Notes

Reaction equation

HRID 948838 reaction equation
[CH2:29]([OH:30])[CH2:31][CH2:32][CH3:33].[CH3:23][NH:24][CH2:25][CH2:26][NH:27][CH3:28].[Cl:2][c:3]1[n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[c:11]([N:13]([CH3:14])[c:15]2[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]2)[n:12]1.[ClH:1]>>[c:3]1([N:24]([CH3:23])[CH2:25][CH2:26][NH:27][CH3:28])[n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[c:11]([N:13]([CH3:14])[c:15]2[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]2)[n:12]1

Participants

5

Reactant 4

HCID 2631-ButanolHCID 313Hydrochloric AcidHCID 8070N,N'-DimethylethylenediamineHCID 117381122-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine

Product 1

HCID 59242059N4-(4-Methoxy-phenyl)-N2,N4-dimethyl-N2-(2-methylamino-ethyl)-quinazoline-2,4-diamine

Sources & evidence

ORD record
ord-f900c1012b8c475b9a41ba7ab2fffa23
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…