Bromide ion → 3-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-(4-fluorophenyl)propan-1-ol
Reaction equation
[Br-:13].[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH3:1][C:2]1([CH3:12])[CH2:3][O:4][CH:5]([CH2:8][CH2:9][CH:10]=[O:11])[O:6][CH2:7]1.[F:14][c:15]1[cH:16][cH:17][c:18]([Mg+:21])[cH:19][cH:20]1>>[CH3:1][C:2]1([CH3:12])[CH2:3][O:4][CH:5]([CH2:8][CH2:9][CH:10]([OH:11])[c:18]2[cH:17][cH:16][c:15]([F:14])[cH:20][cH:19]2)[O:6][CH2:7]1Participants
5
Sources & evidence
- ORD record
- ord-0b0a5b2581fd43ff8950e91a5b9d8a1b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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