Dimethylformamide → N-cyclopropyl-4-methoxy-2-(oxiran-2-ylmethoxy)benzamide

HRID 948923Notes

Reaction equation

HRID 948923 reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[CH:1]1([NH:4][C:5]([c:6]2[c:7]([OH:14])[cH:8][c:9]([O:12][CH3:13])[cH:10][cH:11]2)=[O:15])[CH2:2][CH2:3]1.[Cs+:37].[Cs+:38].[O:16]1[CH:17]([CH2:19][O:20][S:21]([c:22]2[cH:23][cH:24][cH:25][c:26]([N+:27]([O-:28])=[O:29])[cH:30]2)(=[O:31])=[O:32])[CH2:18]1.[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH:1]1([NH:4][C:5]([c:6]2[c:7]([O:14][CH2:19][CH:17]3[O:16][CH2:18]3)[cH:8][c:9]([O:12][CH3:13])[cH:10][cH:11]2)=[O:15])[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 286836(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonateHCID 28390698N-Cyclopropyl-2-hydroxy-4-methoxybenzamide

Product 1

HCID 178491579N-cyclopropyl-4-methoxy-2-(oxiran-2-ylmethoxy)benzamide

Sources & evidence

ORD record
ord-ccb862ac7cda4610938957d79f2edabb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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