Acetic Acid → Tert-butyl 3-(dimethylamino)azetidine-1-carboxylate

HRID 948965Notes

Reaction equation

HRID 948965 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][C:10](=[O:12])[CH2:11]1.[CH3:13][NH:14][CH3:15].[CH3:16][OH:17].[CH3:23][C:24](=[O:25])[OH:26].[O:18]1[CH2:19][CH2:20][CH2:21][CH2:22]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH:10]([N:14]([CH3:13])[CH3:15])[CH2:11]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 674DimethylamineHCID 887MethanolHCID 8028TetrahydrofuranHCID 15194043-Oxo-azetidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 23145930Tert-butyl 3-(dimethylamino)azetidine-1-carboxylate

Sources & evidence

ORD record
ord-fd02d1b087f54025937baadadc34e0ab
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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