Phosphorus oxychloride → 4-Chloro-7-methoxy-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinoline
Reaction equation
[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6](-[c:9]2[n:10][c:11]3[cH:12][c:13]([O:20][CH3:21])[cH:14][cH:15][c:16]3[c:17]([OH:19])[cH:18]2)[s:7][cH:8]1.[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6](-[c:9]2[n:10][c:11]3[cH:12][c:13]([O:20][CH3:21])[cH:14][cH:15][c:16]3[c:17]([Cl:24])[cH:18]2)[s:7][cH:8]1Participants
3
Sources & evidence
- ORD record
- ord-9ef97f9bb962438bb1a863dd6ec25e6f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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