1-Butanol → N-Methyl-2-(4-phenylpiperidin-1-yl)pyrimidin-4-amine
Reaction equation
[CH2:22]([OH:23])[CH2:24][CH2:25][CH3:26].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][CH3:9])[n:7]1.[c:10]1([CH:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[cH:11][cH:12][cH:13][cH:14][cH:15]1>>[c:2]1([N:19]2[CH2:18][CH2:17][CH:16]([c:10]3[cH:11][cH:12][cH:13][cH:14][cH:15]3)[CH2:21][CH2:20]2)[n:3][cH:4][cH:5][c:6]([NH:8][CH3:9])[n:7]1Participants
4
Sources & evidence
- ORD record
- ord-22e6c6ba3d8f459bb5f7c9773a1cf233
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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