Ammonium → 5-(Hydroxymethyl)nicotinonitrile

HRID 949163Notes

Reaction equation

HRID 949163 reaction equation
[CH:13]([Cl:14])([Cl:15])[Cl:16].[Cl-:25].[Cu:10][C:11]#[N:12].[NH4+:23].[NH4+:26].[OH-:24].[OH:1][CH2:2][c:3]1[cH:4][c:5]([Br:9])[cH:6][n:7][cH:8]1.[cH:17]1[cH:18][cH:19][n:20][cH:21][cH:22]1>>[OH:1][CH2:2][c:3]1[cH:4][c:5]([C:11]#[N:12])[cH:6][n:7][cH:8]1

Participants

8

Reactant 7

HCID 223Ammonium2×HCID 312ChlorideHCID 961HydroxideHCID 1049PyridineHCID 6212ChloroformHCID 2784733(5-Bromo-3-pyridinyl)methanolHCID 178418546HCID 178418546, compound

Product 1

HCID 224165405-(Hydroxymethyl)nicotinonitrile

Sources & evidence

ORD record
ord-48d728dd1a7b4f75a6e1bc0eaf58d1a9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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