1-(4-Fluorophenyl)piperazine → N-(1-(4-((4-(4-fluorophenyl)piperazin-1-yl)methyl)phenyl)propyl)acetamide
Reaction equation
[Cl:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([CH:22]([CH2:23][CH3:24])[NH:25][C:26]([CH3:27])=[O:28])[cH:20][cH:21]1.[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH2:15][c:16]3[cH:17][cH:18][c:19]([CH:22]([CH2:23][CH3:24])[NH:25][C:26]([CH3:27])=[O:28])[cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-71b6af8401f0438091c1c7758e4bf6c7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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