Phosphorus oxychloride → 2-Chloro-6-(4-methylphenyl)-5-phenylnicotinonitrile

HRID 949291Notes

Reaction equation

HRID 949291 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:10][c:11]([C:15]#[N:16])[c:12](=[O:14])[nH:13]2)[cH:6][cH:7]1.[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:10][c:11]([C:15]#[N:16])[c:12]([Cl:25])[n:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 211032106-(4-Methylphenyl)-2-oxo-5-phenyl-1,2-dihydropyridine-3-carbonitrile

Product 1

HCID 211031982-Chloro-6-(4-methylphenyl)-5-phenylnicotinonitrile

Sources & evidence

ORD record
ord-0f6056ceee2e4c34aa5081fc84e5f329
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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