Tetrahydrofuran → 3-[-1-(2-fluorophenyl)ethoxy]-5-[6-(hydroxymethyl)-3H-imidazo[4,5-c]pyridin-3-yl]thiophene-2-carboxamide
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14](-[c:17]1[cH:18][c:19]([O:25][CH:26]([CH3:27])[c:28]3[c:29]([F:34])[cH:30][cH:31][cH:32][cH:33]3)[c:20]([C:22](=[O:23])[NH2:24])[s:21]1)[cH:15][n:16]2)([CH3:5])([CH3:35])[CH3:36].[CH2:38]([N+:39]([CH2:40][CH2:41][CH2:42][CH3:43])([CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH2:50][CH3:51])[CH2:52][CH2:53][CH3:54].[CH2:55]1[O:56][CH2:57][CH2:58][CH2:59]1.[F-:37]>>[OH:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14](-[c:17]1[cH:18][c:19]([O:25][CH:26]([CH3:27])[c:28]3[c:29]([F:34])[cH:30][cH:31][cH:32][cH:33]3)[c:20]([C:22](=[O:23])[NH2:24])[s:21]1)[cH:15][n:16]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0a8f52b2a26d43619b0b22701739615b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…