Trifluoroacetic acid → [4-Amino-2-[1-(propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2-methoxy-phenyl)-methanone
Reaction equation
[CH2:32]([CH2:33][CH3:34])[S:35](=[O:36])(=[O:37])[Cl:38].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[n:10][c:11]([NH:25][CH:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[n:12][cH:13][c:14]1[C:15](=[O:16])[c:17]1[c:18]([O:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]1>>[NH2:8][c:9]1[n:10][c:11]([NH:25][CH:26]2[CH2:27][CH2:28][N:29]([S:35]([CH2:32][CH2:33][CH3:34])(=[O:36])=[O:37])[CH2:30][CH2:31]2)[n:12][cH:13][c:14]1[C:15](=[O:16])[c:17]1[c:18]([O:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]1Participants
4
Sources & evidence
- ORD record
- ord-8476564846594bbea58dc2146606669c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…