Sodium ion → (RS)-1-Benzyl-2-(4-phenyl-imidazol-1-ylmethyl)-piperidine

HRID 949783Notes

Reaction equation

HRID 949783 reaction equation
[Br:14][CH2:15][CH:16]1[N:17]([CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:18][CH2:19][CH2:20][CH2:21]1.[H-:12].[Na+:13].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1.[c:1]1(-[c:7]2[n:8][cH:9][nH:10][cH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][cH:9][n:10]([CH2:15][CH:16]3[N:17]([CH2:22][c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:18][CH2:19][CH2:20][CH2:21]3)[cH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 166653HydrideHCID 231462741-Benzyl-2-(bromomethyl)piperidineHCID 178418822HCID 178418822, compound

Product 1

HCID 67158353(RS)-1-Benzyl-2-(4-phenyl-imidazol-1-ylmethyl)-piperidine

Sources & evidence

ORD record
ord-62787d89ca4b4376b8a569307e4fe465
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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