HRID94991

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID8028

Tetrahydrofuran

C4H8O

HCID735900

1-Boc-4-piperidone

C10H17NO3

结构：C[Si](C)(C)CCOCn1cnc(-c2cccc(C(F)(F)F)c2)c1

HCID12114492

未命名化合物

HCID178418339

Butyllithium

C4H9Li

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(O)(c2nc(-c3cccc(C(F)(F)F)c3)cn2COCC[Si](C)(C)C)CC1

HCID66649866

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7836fa5b80f144088a3e69e137c14322
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反应 SMILES

[C:34]([CH3:35])([CH3:36])([CH3:37])[O:38][C:39](=[O:40])[N:41]1[CH2:42][CH2:43][C:44](=[O:47])[CH2:45][CH2:46]1.[CH2:24]([Li:25])[CH2:26][CH2:27][CH3:28].[Cl:48][CH2:49][Cl:50].[F:1][C:2]([c:3]1[cH:4][c:5](-[c:9]2[n:10][cH:11][n:12]([CH2:14][O:15][CH2:16][CH2:17][Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:13]2)[cH:6][cH:7][cH:8]1)([F:22])[F:23].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[F:1][C:2]([c:3]1[cH:4][c:5](-[c:9]2[n:10][c:11]([C:44]3([OH:47])[CH2:43][CH2:42][N:41]([C:39]([O:38][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:40])[CH2:46][CH2:45]3)[n:12]([CH2:14][O:15][CH2:16][CH2:17][Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:13]2)[cH:6][cH:7][cH:8]1)([F:22])[F:23]