Acetic Acid → 8-Ethyl-7-fluoro-1,5-naphthyridin-2(1H)-one
Reaction equation
[BrH:16].[C:17](=[O:18])([O-:19])[OH:20].[CH2:1]([CH3:2])[c:3]1[c:4]([F:15])[cH:5][n:6][c:7]2[cH:8][cH:9][c:10]([O:13][CH3:14])[n:11][c:12]12.[CH3:22][C:23](=[O:24])[OH:25].[Na+:21].[OH2:26]>>[CH2:1]([CH3:2])[c:3]1[c:4]([F:15])[cH:5][n:6][c:7]2[cH:8][cH:9][c:10](=[O:13])[nH:11][c:12]12Participants
7
Sources & evidence
- ORD record
- ord-b79d57baf11d46faa11f4ecce86cf96f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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