Pyridine → 6,8-Difluoro-1,4-dihydro-1-isopropyl-7-(3-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid
Reaction equation
[CH3:21][CH:22]1[NH:23][CH2:24][CH2:25][NH:26][CH2:27]1.[F:1][c:2]1[cH:3][c:4]2[c:5](=[O:20])[c:6]([C:17](=[O:18])[OH:19])[cH:7][n:8]([CH:14]([CH3:15])[CH3:16])[c:9]2[c:10]([F:13])[c:11]1[F:12].[cH:28]1[cH:29][cH:30][n:31][cH:32][cH:33]1>>[F:1][c:2]1[cH:3][c:4]2[c:5](=[O:20])[c:6]([C:17](=[O:18])[OH:19])[cH:7][n:8]([CH:14]([CH3:15])[CH3:16])[c:9]2[c:10]([F:13])[c:11]1[N:26]1[CH2:25][CH2:24][NH:23][CH:22]([CH3:21])[CH2:27]1Participants
4
Sources & evidence
- ORD record
- ord-2554d660910249d19288f08abaf580a4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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