Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950178Generated: October 30, 2026

Hydrochloric Acid → ethyl 2-[[7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]amino]cyclohexane-1-carboxylate

https://huagongshe.com/reaction/950178

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPhosgeneHCID 6371—
ReactantEthyl 2-aminocyclohexanecarboxylateHCID 4171533—
Reactant4-(4-Methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amineHCID 49779438—
Productethyl 2-[[7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]amino]cyclohexane-1-carboxylateHCID 59496738—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9d856adbd51c4b0c961bc694d39b5e44
Source noteValidation data from https://doi.org/10.1039/C8SC04228D