Piperidine → 4-(Piperidin-1-yl)-3-(trifluoromethyl)benzonitrile
Reaction equation
[Br:1][c:2]1[c:3]([C:10]([F:11])([F:12])[F:13])[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[CH2:14]1[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]1>>[c:2]1([N:17]2[CH2:16][CH2:15][CH2:14][CH2:19][CH2:18]2)[c:3]([C:10]([F:11])([F:12])[F:13])[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1Participants
3
Sources & evidence
- ORD record
- ord-42636d0e9d6e4805ae5f0f3c982d516d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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