Ammonium → tert-butyl N-[1-[3-[4-(4-amino-2-fluorophenoxy)-3-pyridinyl]prop-2-enoyl]piperidin-4-yl]carbamate
Reaction equation
[Cl-:36].[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]([CH:11]=[CH:12][C:13](=[O:14])[N:15]3[CH2:16][CH2:17][CH:18]([NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:19][CH2:20]3)[cH:7][n:8][cH:9][cH:10]2)[cH:29][cH:30][c:31]([N+:33]([O-:34])=[O:35])[cH:32]1.[NH4+:37]>>[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]([CH:11]=[CH:12][C:13](=[O:14])[N:15]3[CH2:16][CH2:17][CH:18]([NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:19][CH2:20]3)[cH:7][n:8][cH:9][cH:10]2)[cH:29][cH:30][c:31]([NH2:33])[cH:32]1Participants
4
Sources & evidence
- ORD record
- ord-0aa9f132090f45279cb8c2483c1992cd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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