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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950307Generated: October 28, 2026

Water → 4-Benzyloxy-1-[4-(4-chloro-benzenesulfonyl)-5,8-difluoro-chroman-3-yl]-butan-2-one

https://huagongshe.com/reaction/950307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
Reactant4-(Benzyloxy)butan-2-oneHCID 234511—
Reactant4-((4-Chlorophenyl)sulfonyl)-5,8-difluoro-2H-chromeneHCID 58252242—
ReactantButyllithiumHCID 178418339—
Product4-Benzyloxy-1-[4-(4-chloro-benzenesulfonyl)-5,8-difluoro-chroman-3-yl]-butan-2-oneHCID 67006344—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-ccff4359d06845e09fc4c5f02fddb266
Source noteValidation data from https://doi.org/10.1039/C8SC04228D