Water → 4-Benzyloxy-1-[4-(4-chloro-benzenesulfonyl)-5,8-difluoro-chroman-3-yl]-butan-2-one

HRID 950307Notes

Reaction equation

[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][CH2:21][CH2:22][C:23]([CH3:24])=[O:25].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:53][CH2:54][O:55][C:56](=[O:57])[CH3:58].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl:26][c:27]1[cH:28][cH:29][c:30]([S:33](=[O:34])(=[O:35])[C:36]2=[CH:37][CH2:38][O:39][c:40]3[c:41]([F:47])[cH:42][cH:43][c:44]([F:46])[c:45]32)[cH:31][cH:32]1.[OH2:59]>>[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][CH2:21][CH2:22][C:23]([CH2:24][CH:37]1[CH:36]([S:33]([c:30]2[cH:29][cH:28][c:27]([Cl:26])[cH:32][cH:31]2)(=[O:34])=[O:35])[c:45]2[c:40]([c:41]([F:47])[cH:42][cH:43][c:44]2[F:46])[O:39][CH2:38]1)=[O:25]