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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950540Generated: October 28, 2026

Acetonitrile → [3,5-bis(trifluoromethyl)phenyl]-[2-(1H-indol-3-ylmethyl)-4-(3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropyl)piperazin-1-yl]methanone

https://huagongshe.com/reaction/950540

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant2,3-Dihydrospiro(indene-1,4'-piperidine)HCID 15637616—
Reactant3-[4-[3,5-bis(trifluoromethyl)benzoyl]-3-(1H-indol-3-ylmethyl)piperazin-1-yl]propyl methanesulfonateHCID 178505294—
Product[3,5-bis(trifluoromethyl)phenyl]-[2-(1H-indol-3-ylmethyl)-4-(3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropyl)piperazin-1-yl]methanoneHCID 178519643—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-78b1c7f98f83490b9f51b0608848d697
Source noteValidation data from https://doi.org/10.1039/C8SC04228D