Methanol → 1-Benzyl-4-(2-amino-4-fluorophenylamino)-piperidine
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[c:16]([N+:22]([O-:23])=[O:24])[cH:17][c:18]([F:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:25][OH:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[c:16]([NH2:22])[cH:17][c:18]([F:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-3d9603c9b0e6428d905b6d881f0f69fa
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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