Benzaldehyde → N-(4-Benzylamino-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-acetamide
Reaction equation
[CH2:35]([O:36][CH2:37][CH3:38])[CH3:39].[CH:27](=[O:28])[c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[CH2:16][CH2:17]2)=[O:26])[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[CH2:16][CH2:17]2)=[O:26])[cH:6][cH:7]1)[CH2:27][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1Participants
4
Sources & evidence
- ORD record
- ord-b4c23954edd347848531cdc58195dd19
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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