Dimethylformamide → 3,3,3-trifluoro-N-[3-methyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)cyclopentyl]propane-1-sulfonamide

HRID 950719Notes

Reaction equation

HRID 950719 reaction equation
[F:1][C:2]([CH2:3][CH2:4][S:5](=[O:6])(=[O:7])[Cl:8])([F:9])[F:10].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34].[cH:11]1[cH:12][nH:13][c:14]2[n:15][cH:16][c:17]3[n:18]([c:19]12)[c:20]([CH:23]1[CH2:24][CH:25]([NH2:29])[CH2:26][CH:27]1[CH3:28])[cH:21][n:22]3>>[F:1][C:2]([CH2:3][CH2:4][S:5](=[O:6])(=[O:7])[NH:29][CH:25]1[CH2:24][CH:23]([c:20]2[n:18]3[c:17]([cH:16][n:15][c:14]4[nH:13][cH:12][cH:11][c:19]43)[n:22][cH:21]2)[CH:27]([CH3:28])[CH2:26]1)([F:9])[F:10]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 27611773,3,3-Trifluoropropane-1-sulfonyl chlorideHCID 585571313-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

Product 1

HCID 679980003,3,3-trifluoro-N-[3-methyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)cyclopentyl]propane-1-sulfonamide

Sources & evidence

ORD record
ord-f3f325a904c2475aae3332dc2741b165
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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