Hydrochloric Acid → Hydrochloric Acid

HRID 950745Notes

Reaction equation

HRID 950745 reaction equation
[CH3:22][OH:23].[ClH:21].[O:1]=[C:2]1[NH:3][C:4](=[O:20])[CH2:5][CH2:6][CH:7]1[N:8]1[C:9](=[O:19])[c:10]2[cH:11][cH:12][cH:13][c:14]([C:17]#[N:18])[c:15]2[CH2:16]1>>[ClH:21].[O:1]=[C:2]1[NH:3][C:4](=[O:20])[CH2:5][CH2:6][CH:7]1[N:8]1[C:9](=[O:19])[c:10]2[cH:11][cH:12][cH:13][c:14]([CH2:17][NH2:18])[c:15]2[CH2:16]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 219885472-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindoline-4-carbonitrile

Product 2

HCID 313Hydrochloric AcidHCID 219885693-[4-(Aminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione

Sources & evidence

ORD record
ord-0bbf48ff092a4029a6261c11bc48a740
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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