1-Adamantanecarbonyl chloride → N-phenyl-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-1-adamantanecarboxamide
Reaction equation
[C:22]12([C:32](=[O:33])[Cl:34])[CH2:23][CH:24]3[CH2:25][CH:26]([CH2:27][CH:28]([CH2:29]1)[CH2:30]3)[CH2:31]2.[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[CH2:9][N:10]([CH2:13][CH2:14][c:15]2[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]2)[CH2:11][CH2:12]1>>[N:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([CH:8]1[CH2:9][N:10]([CH2:13][CH2:14][c:15]2[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]2)[CH2:11][CH2:12]1)[C:32]([C:22]12[CH2:23][CH:24]3[CH2:25][CH:26]([CH2:27][CH:28]([CH2:29]1)[CH2:30]3)[CH2:31]2)=[O:33]Participants
3
Sources & evidence
- ORD record
- ord-f0b04d4ebf8b4e139a40efa2f07b0d63
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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