Methylamine → 6-Bromo-8-isopropyl-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([S:11]([CH3:12])=[O:13])[n:8][c:9]2[CH3:10])[n:14]([CH:17]([CH3:18])[CH3:19])[c:15]1=[O:16].[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[CH3:20][NH2:21]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([NH:21][CH3:20])[n:8][c:9]2[CH3:10])[n:14]([CH:17]([CH3:18])[CH3:19])[c:15]1=[O:16]Participants
4
Sources & evidence
- ORD record
- ord-391dbbc0b96648f98bd31e8651493b33
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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