Acetyl chloride → 1-(6-Hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one
Reaction equation
[C:26]([Cl:27])(=[O:28])[CH3:29].[CH2:19]([N:20]([CH2:21][CH3:22])[CH2:23][CH3:24])[CH3:25].[CH3:12][C:13](=[O:14])[O:15][C:16](=[O:17])[CH3:18].[OH:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][NH:7][CH2:6][CH2:5]2>>[OH:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([C:13]([CH3:12])=[O:14])[CH2:6][CH2:5]2Participants
5
Sources & evidence
- ORD record
- ord-ff238d3c8217422fa8a51e14935ba1d2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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