Dimethylformamide → N-(3-fluoro-4-isoquinolin-5-ylphenyl)-1-(2-hydroxypropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxamide

HRID 951067Notes

Reaction equation

[Cl:44][CH2:45][Cl:46].[F:1][c:2]1[cH:3][c:4]([NH2:18])[cH:5][cH:6][c:7]1-[c:8]1[c:9]2[cH:10][cH:11][n:12][cH:13][c:14]2[cH:15][cH:16][cH:17]1.[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[OH:19][CH:20]([CH2:21][n:22]1[n:23](-[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:24](=[O:31])[c:25]([C:28](=[O:29])[OH:30])[c:26]1[CH3:27])[CH3:38]>>[F:1][c:2]1[cH:3][c:4]([NH:18][C:28]([c:25]2[c:24](=[O:31])[n:23](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[n:22]([CH2:21][CH:20]([OH:19])[CH3:38])[c:26]2[CH3:27])=[O:29])[cH:5][cH:6][c:7]1-[c:8]1[c:9]2[cH:10][cH:11][n:12][cH:13][c:14]2[cH:15][cH:16][cH:17]1