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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951110Generated: October 27, 2026

Ammonia → 2-(1-Azetidin-3-yl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenol

https://huagongshe.com/reaction/951110

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantWaterHCID 962—
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-Butyl 3-[5-(5-trifluoromethyl-2-hydroxyphenyl)-1H-pyrazol-1-yl]azetidine-1-carboxylateHCID 136063628—
Product2-(1-Azetidin-3-yl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenolHCID 136063620—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d19134ed944e425bbe5c3b4ada70daab
Source noteValidation data from https://doi.org/10.1039/C8SC04228D