Acetic Acid → 4-(1-Cyclopropyl-7-(((1-methyl-4-phenylpiperidin-4-yl)methoxy)methyl)-1H-indazol-5-yl)benzonitrile

HRID 95121Notes

Reaction equation

HRID 95121 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]3[cH:12][n:13][n:14]([CH:40]4[CH2:41][CH2:42]4)[c:15]3[c:16]([CH2:18][O:19][CH2:20][C:21]3([c:34]4[cH:35][cH:36][cH:37][cH:38][cH:39]4)[CH2:22][CH2:23][N:24]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:25][CH2:26]3)[cH:17]2)[cH:7][cH:8]1.[C:43]([BH3-:44])#[N:45].[CH3:47][C:48](=[O:49])[OH:50].[Na+:46].[OH:51][C:52]([C:53]([F:54])([F:55])[F:56])=[O:57]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]3[cH:12][n:13][n:14]([CH:40]4[CH2:41][CH2:42]4)[c:15]3[c:16]([CH2:18][O:19][CH2:20][C:21]3([c:34]4[cH:35][cH:36][cH:37][cH:38][cH:39]4)[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]3)[cH:17]2)[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 923Sodium ionHCID 6422Trifluoroacetic acidHCID 498716Cyano-borohydrideHCID 57546084HCID 57546084, compound

Product 1

HCID 251605854-(1-Cyclopropyl-7-(((1-methyl-4-phenylpiperidin-4-yl)methoxy)methyl)-1H-indazol-5-yl)benzonitrile

Sources & evidence

ORD record
ord-ac531d78920742488e4838b6d23decec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…