Methanol → 3-(2-(4-fluorobenzoyl)quinazolin-4-ylamino)-1H-pyrazole-5-carbonitrile

HRID 951338Notes

Reaction equation

HRID 951338 reaction equation
[CH3:29][OH:30].[Cl:1][c:2]1[n:3][c:4]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[NH2:21][c:22]1[n:23][nH:24][c:25]([C:27]#[N:28])[cH:26]1.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[c:2]1([NH:21][c:22]2[n:23][nH:24][c:25]([C:27]#[N:28])[cH:26]2)[n:3][c:4]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

5

Reactant 4

HCID 887MethanolHCID 6228DimethylformamideHCID 211805745-Amino-1H-pyrazole-3-carbonitrileHCID 86649048(4-Chloroquinazolin-2-yl)(4-fluorophenyl)methanone

Product 1

HCID 568485463-(2-(4-fluorobenzoyl)quinazolin-4-ylamino)-1H-pyrazole-5-carbonitrile

Sources & evidence

ORD record
ord-b1152628283f41a386b4b5020270085f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…