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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951398Generated: October 26, 2026

Acetic Acid → 4-(3-bromo-2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile

https://huagongshe.com/reaction/951398

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantDimethyl SulfoxideHCID 679—
ReactantSodium ionHCID 923—
ReactantBis(2-chloroethyl) etherHCID 8115—
ReactantEthyl AcetateHCID 8857—
ReactantHydrideHCID 166653—
Reactant(3-Bromo-2-fluorophenyl)acetonitrileHCID 26985257—
Product4-(3-bromo-2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrileHCID 66657493—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-79cbf3d071704cc9a8f7c5b1ebb09d86
Source noteValidation data from https://doi.org/10.1039/C8SC04228D