Toluene → N-(3-methylphenyl)-2-(2-methyl-4-pyridin-2-ylpiperazin-1-yl)acetamide

HRID 951472Notes

Reaction equation

HRID 951472 reaction equation
[Br:14][CH2:15][C:16](=[O:17])[NH:18][c:19]1[cH:20][c:21]([CH3:25])[cH:22][cH:23][cH:24]1.[CH3:1][CH:2]1[CH2:3][N:4]([c:8]2[n:9][cH:10][cH:11][cH:12][cH:13]2)[CH2:5][CH2:6][NH:7]1.[CH3:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34]>>[CH3:1][CH:2]1[CH2:3][N:4]([c:8]2[n:9][cH:10][cH:11][cH:12][cH:13]2)[CH2:5][CH2:6][N:7]1[CH2:15][C:16](=[O:17])[NH:18][c:19]1[cH:20][c:21]([CH3:25])[cH:22][cH:23][cH:24]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 81531DiisopropylethylamineHCID 2255282-bromo-N-(3-methylphenyl)acetamideHCID 118491873-Methyl-1-pyridin-2-yl-piperazine

Product 1

HCID 68876170N-(3-methylphenyl)-2-(2-methyl-4-pyridin-2-ylpiperazin-1-yl)acetamide

Sources & evidence

ORD record
ord-aeed3e1f461c41de9ae723c6a7cda48a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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