Methanol → 3-(2-Nitrobenzylamino)-1-phenylpropanol

HRID 951595Notes

Reaction equation

HRID 951595 reaction equation
[BH3:28].[CH3:34][OH:35].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1.[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH:1][CH:2]([CH2:3][C:4](=[O:5])[NH:6][CH2:7][c:8]1[c:9]([N+:14](=[O:15])[O-:16])[cH:10][cH:11][cH:12][cH:13]1)[c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1>>[OH:1][CH:2]([CH2:3][CH2:4][NH:6][CH2:7][c:8]1[c:9]([N+:14](=[O:15])[O-:16])[cH:10][cH:11][cH:12][cH:13]1)[c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6331BoraneHCID 8028Tetrahydrofuran3×HCID 674618943-hydroxy-N-(2-nitrobenzyl)-3-phenyl propionic acid amide

Product 1

HCID 674614753-(2-Nitrobenzylamino)-1-phenylpropanol

Sources & evidence

ORD record
ord-6d511189cb4542f2803af7629761aee9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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