Ethylenediamine → 2-[(2-Aminoethyl)amino]-4-(2,4-difluorophenyl)-8-(2-fluorophenyl)pyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[F:1][c:2]1[c:3](-[c:9]2[c:10]3[c:11]([n:12][c:13]([S:15]([CH3:16])(=[O:17])=[O:18])[n:14]2)[n:19](-[c:24]2[c:25]([F:30])[cH:26][cH:27][cH:28][cH:29]2)[c:20](=[O:23])[cH:21][cH:22]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[NH2:31][CH2:32][CH2:33][NH2:34]>>[F:1][c:2]1[c:3](-[c:9]2[c:10]3[c:11]([n:12][c:13]([NH:34][CH2:33][CH2:32][NH2:31])[n:14]2)[n:19](-[c:24]2[c:25]([F:30])[cH:26][cH:27][cH:28][cH:29]2)[c:20](=[O:23])[cH:21][cH:22]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-fb3ba99729de4330bc62125e248746d0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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