Water → 1-(5-amino-pyrazin-2-yl)-ethanone O-tert-butyl-oxime

HRID 951775Notes

Reaction equation

HRID 951775 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][N:6]=[C:7]([CH3:8])[c:9]1[n:10][cH:11][c:12]([NH:15][C:16](=[O:17])[C:18]([CH3:19])([CH3:20])[CH3:21])[n:13][cH:14]1.[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[NH2:29][NH2:30].[O:22]1[CH2:23][CH2:24][O:25][CH2:26][CH2:27]1.[OH2:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][N:6]=[C:7]([CH3:8])[c:9]1[n:10][cH:11][c:12]([NH2:15])[n:13][cH:14]1

Participants

6

Reactant 5

HCID 962WaterHCID 8857Ethyl AcetateHCID 9321HydrazineHCID 312751,4-DioxaneHCID 73852558N-[5-(1-tert-butoxyimino-ethyl)-pyrazin-2-yl]-2,2-dimethyl-propionamide

Product 1

HCID 865937831-(5-amino-pyrazin-2-yl)-ethanone O-tert-butyl-oxime

Sources & evidence

ORD record
ord-cf728df4ea73419abc72907f314f6b1b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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