Dichloromethane → Ethyl 2-methyl-1-piperazinecarboxylate

HRID 951807Notes

Reaction equation

HRID 951807 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH:7]([CH3:19])[CH2:8][N:9]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:10][CH2:11]1.[Cl:27][CH2:28][Cl:29].[F:20][C:21]([F:22])([F:23])[C:24]([OH:25])=[O:26]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH:7]([CH3:19])[CH2:8][NH:9][CH2:10][CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 771974934-O-tert-butyl 1-O-ethyl 2-methylpiperazine-1,4-dicarboxylate

Product 1

HCID 14722554Ethyl 2-methyl-1-piperazinecarboxylate

Sources & evidence

ORD record
ord-0e8191ea06c94766a9f0933969f34d24
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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